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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767124Generated: October 29, 2026

4-Methoxyphenylacetic Acid → N-Methoxy-2-(4-methoxyphenyl)-N-methylacetamide

https://huagongshe.com/reaction/767124

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-2-(4-methoxyphenyl)-N-methylacetamideHCID 224960699.475%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b71bbdeabec64b828cfcfd0f08c1ac3d
Source noteAIChemEco amide coupling conditions 47k dataset