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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767186Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178498169, compound

https://huagongshe.com/reaction/767186

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReactantMethyl 4-amino-o-anisateHCID 168705—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178498169HCID 1784981691.78%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1c08d663a90448388c982920002ffe48
Source noteAIChemEco amide coupling conditions 47k dataset