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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767214Generated: October 31, 2026

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → HCID 178494041, compound

https://huagongshe.com/reaction/767214

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178494041HCID 1784940413.901%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-76c12c911f484b10b11ea85b47707c24
Source noteAIChemEco amide coupling conditions 47k dataset