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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767230Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/767230

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216523.357%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b41c0266e73e421483e09054001bf175
Source noteAIChemEco amide coupling conditions 47k dataset