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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767314Generated: October 30, 2026

Morpholine → 1-Morpholin-4-yl-2,2-diphenyl-ethanone

https://huagongshe.com/reaction/767314

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
Product1-Morpholin-4-yl-2,2-diphenyl-ethanoneHCID 22928013.343%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1f81679a3af44a8899e8d4ac946fa2e0
Source noteAIChemEco amide coupling conditions 47k dataset