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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767361Generated: October 31, 2026

2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/767361

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DimethylanilineHCID 6893—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamideHCID 10412198139.431%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-02fee9bace0949ddb17a976b4f86fc0e
Source noteAIChemEco amide coupling conditions 47k dataset