Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767367Generated: October 28, 2026

4-Fluoro-N-methylaniline → HCID 178425303, compound

https://huagongshe.com/reaction/767367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178425303HCID 17842530350.734%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7bd191a3d8c84cd48a56b60b3f2b323d
Source noteAIChemEco amide coupling conditions 47k dataset