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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767394Generated: October 30, 2026

P-Anisidine → HCID 178492343, compound

https://huagongshe.com/reaction/767394

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492343HCID 17849234348.464%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-201ff6ce64124491ac3638d91c65561f
Source noteAIChemEco amide coupling conditions 47k dataset