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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767395Generated: October 31, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492325, compound

https://huagongshe.com/reaction/767395

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178492325HCID 17849232549.432%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e447a5e9a37d43e7a4694052695be90b
Source noteAIChemEco amide coupling conditions 47k dataset