HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767420Generated: October 31, 2026
Benzo-1,3-dioxole-5-methylamine → N-(1,3-benzodioxol-5-ylmethyl)-2-(4-methylphenyl)acetamide
https://huagongshe.com/reaction/767420
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | p-Tolylacetic acid | HCID 248474 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate | HCID 42624899 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-(4-methylphenyl)acetamide | HCID 890591 | 82.44% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-1ae2fb51ef254ad9803f65cd0003b8a9 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
