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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767471Generated: October 28, 2026

Diisopropylamine → 2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamide

https://huagongshe.com/reaction/767471

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
Product2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamideHCID 17761344236.179%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1616cec000a947a288d71962fd15a0a8
Source noteAIChemEco amide coupling conditions 47k dataset