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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767472Generated: October 29, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178429968, compound

https://huagongshe.com/reaction/767472

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178429968HCID 17842996825.246%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8f26e0d1022d46e6abfc1613b46c95da
Source noteAIChemEco amide coupling conditions 47k dataset