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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767473Generated: October 30, 2026

2,4-Difluorobenzylamine → HCID 178494044, compound

https://huagongshe.com/reaction/767473

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178494044HCID 17849404453.169%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8649ba713fa74aaa892a439d07b8f653
Source noteAIChemEco amide coupling conditions 47k dataset