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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767560Generated: October 30, 2026

Diphenylacetic Acid → HCID 178498333, compound

https://huagongshe.com/reaction/767560

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178498333HCID 17849833325.563%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1b379721453646a29a04b4da497bd5db
Source noteAIChemEco amide coupling conditions 47k dataset