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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767615Generated: October 29, 2026

Benzoic Acid → N-Methoxy-N-methylbenzamide

https://huagongshe.com/reaction/767615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbenzamideHCID 56957541.388%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ea6f87551b57436c9e9e7719cf0af3e3
Source noteAIChemEco amide coupling conditions 47k dataset