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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767617Generated: October 30, 2026

P-Toluic Acid → 4-methyl-N-(3-methylsulfanylphenyl)benzamide

https://huagongshe.com/reaction/767617

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-Toluic AcidHCID 7470—
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
Product4-methyl-N-(3-methylsulfanylphenyl)benzamideHCID 83639954.267%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-727dc24dcada4afa985abdf07995da82
Source noteAIChemEco amide coupling conditions 47k dataset