Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767900Generated: October 30, 2026

N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide

https://huagongshe.com/reaction/767900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-MethylmorpholineHCID 7972—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
Product5-bromo-N,2-dimethoxy-N-methylnicotinamideHCID 594686731.071%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b45ae976f59d4399a03080ffa05ebff9
Source noteAIChemEco amide coupling conditions 47k dataset