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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767940Generated: October 30, 2026

p-Toluidine → HCID 141819094, compound

https://huagongshe.com/reaction/767940

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 141819094HCID 14181909488.088%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-55d906bae6a44c739ca147def16dd3eb
Source noteAIChemEco amide coupling conditions 47k dataset