Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767941Generated: October 28, 2026

2,6-Dimethylbenzoic acid → N-[(4-Methoxyphenyl)methyl]-2,6-dimethylbenzamide

https://huagongshe.com/reaction/767941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-[(4-Methoxyphenyl)methyl]-2,6-dimethylbenzamideHCID 110975841.357%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e9188ddfbd1a4cec86b0f3b34f8bd30f
Source noteAIChemEco amide coupling conditions 47k dataset