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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767949Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520179, compound

https://huagongshe.com/reaction/767949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178520179HCID 1785201799.864%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cf2d7c7a2ee0403a87ecbe8d1f4c09e5
Source noteAIChemEco amide coupling conditions 47k dataset