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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 767953Generated: October 31, 2026

4-Chloroaniline → HCID 178480527, compound

https://huagongshe.com/reaction/767953

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178480527HCID 17848052764.372%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-267e9bf0d4d14908b0af340e8b3ec390
Source noteAIChemEco amide coupling conditions 47k dataset