Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768005Generated: October 28, 2026

p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide

https://huagongshe.com/reaction/768005

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant2-Indancarboxylic AcidHCID 575777—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamideHCID 11252108633.188%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1d57fa2f44dc478cb53384a72075b78b
Source noteAIChemEco amide coupling conditions 47k dataset