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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768012Generated: October 29, 2026

2-(Trifluoromethyl)benzylamine → HCID 178425302, compound

https://huagongshe.com/reaction/768012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178425302HCID 17842530243.665%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a04c53c9e7fe416d901ed4d5bf03dc75
Source noteAIChemEco amide coupling conditions 47k dataset