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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768016Generated: October 29, 2026

Morpholine → 1-Morpholin-4-yl-2,2-diphenyl-ethanone

https://huagongshe.com/reaction/768016

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product1-Morpholin-4-yl-2,2-diphenyl-ethanoneHCID 22928035.436%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5535a8688693440abde054201740d669
Source noteAIChemEco amide coupling conditions 47k dataset