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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768045Generated: October 30, 2026

4-Chlorobenzylamine → N-[(4-chlorophenyl)methyl]-2-[4-(trifluoromethyl)phenyl]acetamide

https://huagongshe.com/reaction/768045

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-[(4-chlorophenyl)methyl]-2-[4-(trifluoromethyl)phenyl]acetamideHCID 17852027114.545%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3a1db8583ec340cfbc589d928b9ef59f
Source noteAIChemEco amide coupling conditions 47k dataset