Sulfuryl chloride → 2-Chloro-3-(3-oxomorpholino)benzene-1-sulfonyl chloride

HRID 76805Notes

Reaction equation

HRID 76805 reaction equation
C(S[C:9]1[C:10]([Cl:22])=[C:11]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][C:16]2=[O:21])[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1.[S:23]([Cl:27])(Cl)(=[O:25])=[O:24]>>[Cl:22][C:10]1[C:11]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][C:16]2=[O:21])=[CH:12][CH:13]=[CH:14][C:9]=1[S:23]([Cl:27])(=[O:25])=[O:24]

Participants

3

Reactant 2

HCID 24648Sulfuryl chlorideHCID 669111644-(3-(Benzylthio)-2-chlorophenyl)morpholin-3-one

Product 1

HCID 727929542-Chloro-3-(3-oxomorpholino)benzene-1-sulfonyl chloride

Procedure

Intermediate 10 (1 g, 3.05 mmol) was converted to the title sulfonyl chloride using the procedure described in example 1; 1.6). The crude material was used without further purification in the next step.

Workup

  1. customThe crude material was used without further purification in the next step

Sources & evidence

ORD record
ord-52c3bb1605b04288803e6791658d757d
Source dataset
uspto-grants-2014_09
Patent number
US08835653B2

Reaction notes

Loading…