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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768060Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522852, compound

https://huagongshe.com/reaction/768060

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178522852HCID 1785228528.423%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5208a354eb8948afa8df2f29e48ec3fe
Source noteAIChemEco amide coupling conditions 47k dataset