反应详情

Intermediate 13 (4.22 g, 12.9 mmol) was treated with piperidin-2-one (1.41 g, 14.2 mmol) according to the procedure described in 1.5). Yield after triturating (with n-heptane-ethyl acetate, 4:1) and filtration: 2.67 g (60%), crystalline solid.

1. customYield
2. customafter triturating
3. filtration(with n-heptane-ethyl acetate, 4:1) and filtration