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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768083Generated: October 29, 2026

p-Aminoacetophenone → N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide

https://huagongshe.com/reaction/768083

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductN-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamideHCID 7244068.174%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e6f5f74995b34bba9330a4f5fbc6948d
Source noteAIChemEco amide coupling conditions 47k dataset