HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 5-Fluoro-2-methoxy-3-(2-oxo-piperidin-1-yl)benzenesulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 1-(3-Benzylsulfanyl-5-fluoro-2-methoxy-phenyl)piperidin-2-one | HCID 66911163 | — |
| Product | 5-Fluoro-2-methoxy-3-(2-oxo-piperidin-1-yl)benzenesulfonyl chloride | HCID 86653268 | — |
Reaction Steps
Intermediate 14 (1.6 g, 4.63 mmol) was converted to the title compound sulfonyl chloride using the procedure described in example 1; 1.6). The crude material was used without further purification in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835653B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-92068e1b236f472f8792bddb3d9e6952 |
| Source note | uspto-grants-2014_09 |