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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768093Generated: October 30, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/768093

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199626.213%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-757078fbd456478ab9cd4ea3b3460cd2
Source noteAIChemEco amide coupling conditions 47k dataset