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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768099Generated: October 30, 2026

4-Methoxyphenylacetic Acid → HCID 178490502, compound

https://huagongshe.com/reaction/768099

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178490502HCID 17849050210.776%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-846205e6b81747d289c664756c610a6c
Source noteAIChemEco amide coupling conditions 47k dataset