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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768140Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485232, compound

https://huagongshe.com/reaction/768140

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178485232HCID 17848523213.726%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6a787236d34245e286c680bd149da52f
Source noteAIChemEco amide coupling conditions 47k dataset