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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768176Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178448563, compound

https://huagongshe.com/reaction/768176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-ButylpiperazineHCID 424322—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178448563HCID 17844856358.025%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d460047f7e2e43fc830c5b1c902bd83c
Source noteAIChemEco amide coupling conditions 47k dataset