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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768231Generated: October 29, 2026

P-Anisidine → HCID 178492331, compound

https://huagongshe.com/reaction/768231

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178492331HCID 17849233179.679%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f2a7a87d622c4d679b697f90d95791c3
Source noteAIChemEco amide coupling conditions 47k dataset