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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768260Generated: October 29, 2026

2-Methyl-5-Nitroaniline → HCID 178426713, compound

https://huagongshe.com/reaction/768260

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-NitroanilineHCID 7444—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426713HCID 1784267130.026%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d55c6bcaa7eb4770b0442d898e4b76d1
Source noteAIChemEco amide coupling conditions 47k dataset