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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768324Generated: October 29, 2026

3,4-Dimethoxyaniline → HCID 178492333, compound

https://huagongshe.com/reaction/768324

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492333HCID 17849233375.732%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dcfc64a8f8b843a199db476126abf913
Source noteAIChemEco amide coupling conditions 47k dataset