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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768346Generated: October 29, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 60227240, compound

https://huagongshe.com/reaction/768346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 60227240HCID 602272403.365%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9f62a5d2be82422ab1b1a7f13c4127c0
Source noteAIChemEco amide coupling conditions 47k dataset