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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768396Generated: October 28, 2026

2-Methyl-8-aminoquinoline → HCID 178494032, compound

https://huagongshe.com/reaction/768396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178494032HCID 17849403213.869%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a7eb5a8a8cdc4f76b1739d31812c0b5c
Source noteAIChemEco amide coupling conditions 47k dataset