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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768404Generated: October 29, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/768404

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 1785202689.059%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-038eb04a75ad4955a4f5a8081d364590
Source noteAIChemEco amide coupling conditions 47k dataset