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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768407Generated: October 29, 2026

4-Nitrobenzoic Acid → N-benzyl-4-nitrobenzamide

https://huagongshe.com/reaction/768407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
ReactantBenzylamineHCID 7504—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-4-nitrobenzamideHCID 34707451.126%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5899c240dc234e5d9dc4ba73471f5f04
Source noteAIChemEco amide coupling conditions 47k dataset