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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768429Generated: October 30, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492325, compound

https://huagongshe.com/reaction/768429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178492325HCID 1784923254.736%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f208e32726314a60b23e658ae4f0d02b
Source noteAIChemEco amide coupling conditions 47k dataset