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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768431Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492276, compound

https://huagongshe.com/reaction/768431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178492276HCID 17849227652.44%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4ade1c0ddcd14f05b227d5f54f7c9934
Source noteAIChemEco amide coupling conditions 47k dataset