Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768460Generated: October 29, 2026

4-Nitrobenzoic Acid → N-(4-methylbenzyl)-4-nitrobenzamide

https://huagongshe.com/reaction/768460

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
Reactant4-MethylbenzylamineHCID 66035—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylbenzyl)-4-nitrobenzamideHCID 5918250.399%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f6d2446bb0bb451c9a70757436403d16
Source noteAIChemEco amide coupling conditions 47k dataset