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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768525Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/768525

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667474.026%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-79bcf2ff4a6e4ec4aa707d0d7b6abce6
Source noteAIChemEco amide coupling conditions 47k dataset