N-bromobutanimide → HCID 58827061, compound

HRID 76853Notes

Reaction equation

HRID 76853 reaction equation
[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[O:10][C:11]([F:14])([F:13])[F:12].C1C(=O)N([Br:22])C(=O)C1>>[Br:22][CH2:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[O:10][C:11]([F:12])([F:13])[F:14]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 58999564HCID 58999564, compound

Product 1

HCID 58827061HCID 58827061, compound

Procedure

4-Methyl-3-Trifluoromethoxybenzonitrile is brominated with NBS according to Example 1A to give 4-bromomethyl-3-trifluoromethoxybenzonitrile. 1H NMR (400 MHz, CDCl3) δ (ppm) 4.51 (s, 2H), 7.55 (br s, 1H), 7.59 (d, J=8.0 Hz, 1H), 7.64 (d, J=8.0 Hz, 1H).

Sources & evidence

ORD record
ord-720b06478b1f4ef19ed8226886f50a6d
Source dataset
uspto-grants-2014_09
Patent number
US08835646B2

Reaction notes

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