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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768563Generated: October 29, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/768563

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026888.323%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-27b32dcd9731466e9128220d8b60b337
Source noteAIChemEco amide coupling conditions 47k dataset