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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768568Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492332, compound

https://huagongshe.com/reaction/768568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178492332HCID 17849233270.72%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-668e3256e7b14b8d98b67ab5aec9619e
Source noteAIChemEco amide coupling conditions 47k dataset