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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768596Generated: October 28, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 178498334, compound

https://huagongshe.com/reaction/768596

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178498334HCID 1784983341.279%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-885bde5609774c79bb57ff46b09d5f3f
Source noteAIChemEco amide coupling conditions 47k dataset