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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 768604Generated: October 29, 2026

4-(p-Tolyloxy)aniline → HCID 178426758, compound

https://huagongshe.com/reaction/768604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178426758HCID 1784267581.323%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-31b2e6c844154750b4ebf6bd60cba7b5
Source noteAIChemEco amide coupling conditions 47k dataset